Elżbieta Sochacka's Research Group

 

          

 

Contact


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ORCID: https://orcid.org/0000-0002-9020-8299

 

Publications


 

Different Oxidation Pathways of 2-Selenouracil and 2-Thiouracil, Natural Components of Transfer RNA.

Kulik, K., Sadowska, K., Wielgus, E., Pacholczyk-Sienicka, B., Sochacka, E., Nawrot, B. Int. J. Mol. Sci. 2020, 21(17), 5956.

 

C5-Substituted 2-Selenouridines Ensure Efficient Base Pairing with Guanosine; Consequences for Reading the NNG-3' Synonymous mRNA Codons.

Leszczynska, G., Cypryk, M., Gostynski, B., Sadowska, K., Herman. P., Bujacz, G., Lodyga-Chuscinska, E., Sochacka, E., Nawrot, B. Int. J. Mol. Sci. 2020, 21(8), 2882.

 

Escherichia coli tRNA 2-selenouridine synthase (SeIU) converts S2U-RNA to Se2U-RNA via S-geranylated-intermediate.

Sierant, M., Leszczynska, G., Sadowska, K., Komar, P., Radzikowska-Cieciura, E., Sochacka, E., Nawrot, B. FEBS Lett. 2018, 592(13), 2248-2258.

 

Reaction of S-geranyl-2-thiouracil modified oligonucleotides with alkyl amines leads to the N2-alkyl isocytosine derivatives.

Leszczynska, G., Sadowska, K., Sierant, M., Sobczak, M., Nawrot, B., Sochacka, E. Org. Biomol. Chem. 201715(25), 5332-5336.

 

S-Geranyl-2-thiouridine wobble nucleosides of bacterial tRNAs; chemical and enzymatic synthesis of S-geranylated-RNAs and their physicochemical characterization.

Sierant, M., Leszczynska, G., Sadowska, K., Dziergowska, A., Rozanski, M., Sochacka, E., Nawrot, B., Nucleic Acids Res. 201644(22), 10986-10998.
 

S-Geranylated 2-Thiouridines of Bacterial tRNAs: Chemical Synthesis and Physicochemical Properties.

Leszczynska, G., Sadowska, K., Bartos, P., Nawrot, B., Sochacka, E. Eur. J. Org. Chem. 201621, 3482-3485.