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ORCID: https://orcid.org/0000-0001-8094-6741

Publications

Synthesis of Nucleobase-Modified RNA Oligonucleotides by Post-Synthetic Approach.

Bartosik, K., Debiec, K., Czarnecka, A., Sochacka, E., Leszczynska, G. Molecules 2020, 25(15), 3344

Post-synthetic conversion of 5-pivaloyloxymethyluridine present in a support-bound RNA oligomer into biologically relevant derivatives of 5-methyluridine.

Bartosik, K., Sochacka, E., Leszczynska, G. Org. Biomol. Chem. 2017, 15(9), 2097-2103.

Synthesis of various substituted 5-methyluridines (xm5U) and 2-thiouridines (xm5s2U) via nucleophilic substitution of 5-pivaloyloxymethyluridine/2-thiouridine.

Bartosik, K., Leszczynska, G.,Tetrahedron Lett., 2015, 56, 6593-6597.

Chemical synthesis of the 5-taurinomethyl(-2-thio)uridine modified anticodon arm of the human mitochondrial tRNA^Leu(UUR) and tRNA^Lys.

Leszczyńska, G., Leonczak P., Wozniak, K., Malkiewicz, A. RNA 2014,20, 938-947.

Site-selected incorporation of 5-carboxymethylaminomethyl(-2-thio)uridine into RNA sequences by phosphoramidite chemistry.

Leszczynska, G., Pięta, J., Wozniak, K., Malkiewicz, A. Org. Biomol. Chem. 2014, 12, 1052-1056. 

Chemical synthesis of human mitochondrial tRNA^lys fragment containing 5-taurinomethyl-2-thiouridine and 6-threonylcarbamoyladenosine.

Wozniak, K., Stasiak, A., Leonczak, P., Leszczynska, G., Malkiewicz, A., Coll. Czech. Chem. Commun., Symp. Series, 2014, 14, 408-410.