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ORCID: https://orcid.org/0000-0002-8888-380X

Publications

Nano LC-MS using capillary columns enables accurate quantification of modified ribonucleosides at low femtomol levels.

Sarin, LP., Kienast, SD., Leufken, J.,  Ross, RL., Dziergowska, A., Debiec, K., Sochacka, E., Limbach, PA., Fufezan, C., Drexler, HCA., Leidel, SA. RNA 2018, 24(10), 1403-1417.

S-Geranyl-2-thiouridine wobble nucleosides of bacterial tRNAs; chemical and enzymatic synthesis of S-geranylated-RNAs and their physicochemical characterization.

Sierant, M., Leszczynska, G., Sadowska, K., Dziergowska, A., Rozanski, M., Sochacka, E., Nawrot, B., Nucleic Acids Res. 2016, 44(22), 10986-10998.

tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence.

Chionh, Y. H., McBee, M., Babu, I. R., Hia, F. B., Lin, W. W., Zhao, W., Cao, J. S., Dziergowska, A., Malkiewicz, A., Begley, T. J., Alonso, S., Dedon, P. C. Nat. Commun. 2016, 13302(7), 1-12.

Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage.

Endres, L., Begley, U., Clark, R., Gu, C., Dziergowska, A., Malkiewicz, A., Melendez, J. A., Dedon, P. C., Begley, T. J.,PLOS ONE, 2015, 10(7), 1-23.

mt-tRNA components: synthesis of (2-thio)uridines modified with blocked glycine/taurine moieties at C-5,1.

Leszczynska, G., Leonczak, P., Dziergowska, A., Malkiewicz, A. Nucleosides, Nucleotides and Nucleic Acids 2013, 32, 599-616. 

3-(3-amino-3-carboxypropyl)-5,6-Dihydrouridine is one of two novel post-transcriptional modifications in tRNALys(UUU) from Trypanosoma brucei.

Krog, J. S., Espanol, Y., Giessing, A. M. B., Dziergowska, A., Malkiewicz, A., de Pouplana, L. R., Kirpekar, F. FEBS JOURNAL, 2011, 278(24), 4782-4796.

Anticodon domain modifications contribute order to tRNA for ribosome-mediated codon binding.

Vendeix, F. A P., Dziergowska, A., Gustilo, E. M., Graham, W. D., Sproat, B., Malkiewicz, A., Agris, P.F. BIOCHEMISTRY, 2008, 47(23), 6117-6129.

Mechanism for expanding the decoding capacity of transfer RNAs by modification of uredines.

Weixlbaumer A., Murphy F. V., Dziergowska A., Malkiewicz A., Vendeix F. A. P., Agris P. F., Ramakrishnan V. NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2007, 14(6), 498-502.